Corneal Absorption of a New Riboflavin-Nanostructured System for Transepithelial Collagen Cross-Linking
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چکیده
منابع مشابه
Corneal Absorption of a New Riboflavin-Nanostructured System for Transepithelial Collagen Cross-Linking
Corneal collagen cross-linking (CXL) has been described as a promising therapy for keratoconus. According to standard CXL protocol, epithelium should be debrided before treatment to allow penetration of riboflavin into the corneal stroma. However, removal of the epithelium can increase procedure risks. In this study we aim to evaluate stromal penetration of a biocompatible riboflavin-based nano...
متن کاملcross-linking of corneal collagen with uva and riboflavin for the treatment of corneal disease
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متن کاملTransepithelial corneal collagen cross-linking in ultrathin keratoconic corneas
BACKGROUND The purpose of this paper was to report the results of transepithelial corneal collagen cross-linking (CXL) with modified riboflavin and ultraviolet A irradiation in patients affected by keratoconus, each with thinnest pachymetry values of less than 400 μm (with epithelium) and not treatable using standard de-epithelialization techniques. METHODS Sixteen patients affected by progre...
متن کاملUVA-light and riboflavin-mediated corneal collagen cross-linking.
Keratoconus and other corneal conditions associated with progressive stromal thinning including keratectasia after laser-assisted in situ keratomileusis (LASIK) and pellucid marginal degeneration represent therapeutic challenges. Until recently, available therapies including contact lenses, epikeratoplasty, intrastromal corneal rings, and corneal transplantation targeted, in principle, the abno...
متن کاملHistopathological Finding of Cornea after Collagen Cross-Linking Using Riboflavin and Ultraviolet A in Rabbit
Purpose: To evaluate the histopathological changes of the cornea in rabbit corneas after accelerated collagen cross-linking. Methods: Right eyes of 7 adult New Zealand albino rabbits weighing 1.5 to 2.0 kg were studied. Right eyes of all animals were in the treatment group and left eyes were in the control group. The epithelium of all right eyes was removed and was crossed-linked with riboflavi...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0066408